β Cell Hypoxia-Inducible Factor-1 α Is Required for the Prevention of Type 1 Diabetes

The development of autoimmune disease type 1 diabetes (T1D) is determined by both genetic background and environmental factors. Environmental triggers include RNA viruses, particularly coxsackie-virus (CV), but how they induceT1D is not understood. Here, we demonstrate that deletion of the transcrip...

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Foilsithe in:Cell Rep
Main Authors: Lalwani, Amit, Warren, Joanna, Liuwantara, David, Hawthorne, Wayne J., O’Connell, Philip J., Gonzalez, Frank J., Stokes, Rebecca A., Chen, Jennifer, Laybutt, D. Ross, Craig, Maria E., Swarbrick, Michael M., King, Cecile, Gunton, Jenny E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2019
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6661122/
https://ncbi.nlm.nih.gov/pubmed/31116982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.04.086
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