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Immunological Features with DNA Microsatellite Alterations in Patients with Colorectal Cancer

Competent human DNA mismatch repair (MMR) corrects DNA polymerase mistakes made during cell replication to maintain complete DNA fidelity in daughter cells; faulty DNA MMR occurs in the setting of inflammation and neoplasia, creating base substitutions (e.g. point mutations) and frameshift mutations...

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Veröffentlicht in:J Cancer Immunol (Wilmington)
Hauptverfasser: Raeker, Maide O., Carethers, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523708/
https://ncbi.nlm.nih.gov/pubmed/33000102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33696/cancerimmunol.2.024
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