Fusobacterium nucleatum infection correlates with two types of microsatellite alterations in colorectal cancer and triggers DNA damage

Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylation phenotype (CIMP). Fn infection is also associated with the inflammatory tumor microenv...

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Dades bibliogràfiques
Publicat a:Gut Pathog
Autors principals: Okita, Yoshiki, Koi, Minoru, Takeda, Koki, Ross, Ryan, Mukherjee, Bhramar, Koeppe, Erika, Stoffel, Elena M., Galanko, Joseph A., McCoy, Amber N., Keku, Temitope O., Okugawa, Yoshinaga, Kitajima, Takahito, Toiyama, Yuji, Martens, Eric, Carethers, John M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Letter to the Editor
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526104/
https://ncbi.nlm.nih.gov/pubmed/33005238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13099-020-00384-3
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