Fusobacterium nucleatum infection correlates with two types of microsatellite alterations in colorectal cancer and triggers DNA damage

Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylation phenotype (CIMP). Fn infection is also associated with the inflammatory tumor microenv...

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Dettagli Bibliografici
Pubblicato in:Gut Pathog
Autori principali: Okita, Yoshiki, Koi, Minoru, Takeda, Koki, Ross, Ryan, Mukherjee, Bhramar, Koeppe, Erika, Stoffel, Elena M., Galanko, Joseph A., McCoy, Amber N., Keku, Temitope O., Okugawa, Yoshinaga, Kitajima, Takahito, Toiyama, Yuji, Martens, Eric, Carethers, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Letter to the Editor
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526104/
https://ncbi.nlm.nih.gov/pubmed/33005238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13099-020-00384-3
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