Fusobacterium nucleatum infection correlates with two types of microsatellite alterations in colorectal cancer and triggers DNA damage

Fusobacterium nucleatum (Fn) is frequently found in colorectal cancers (CRCs). High loads of Fn DNA are detected in CRC tissues with microsatellite instability-high (MSI-H), or with the CpG island hypermethylation phenotype (CIMP). Fn infection is also associated with the inflammatory tumor microenv...

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Detalhes bibliográficos
Publicado no:Gut Pathog
Main Authors: Okita, Yoshiki, Koi, Minoru, Takeda, Koki, Ross, Ryan, Mukherjee, Bhramar, Koeppe, Erika, Stoffel, Elena M., Galanko, Joseph A., McCoy, Amber N., Keku, Temitope O., Okugawa, Yoshinaga, Kitajima, Takahito, Toiyama, Yuji, Martens, Eric, Carethers, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526104/
https://ncbi.nlm.nih.gov/pubmed/33005238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13099-020-00384-3
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