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Immunological Features with DNA Microsatellite Alterations in Patients with Colorectal Cancer

Competent human DNA mismatch repair (MMR) corrects DNA polymerase mistakes made during cell replication to maintain complete DNA fidelity in daughter cells; faulty DNA MMR occurs in the setting of inflammation and neoplasia, creating base substitutions (e.g. point mutations) and frameshift mutations...

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Bibliografische gegevens
Gepubliceerd in:J Cancer Immunol (Wilmington)
Hoofdauteurs: Raeker, Maide O., Carethers, John M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523708/
https://ncbi.nlm.nih.gov/pubmed/33000102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33696/cancerimmunol.2.024
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