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Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis
Anterior gradient 2 (AGR2) is a member of the protein disulfide isomerase (PDI) family, which plays a role in the regulation of protein homeostasis and the unfolded protein response pathway (UPR). AGR2 has also been characterized as a proto-oncogene and a potential cancer biomarker. Cellular localiz...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523706/ https://ncbi.nlm.nih.gov/pubmed/30575818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0638-9 |
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