Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Anterior gradient 2 (AGR2) is a member of the protein disulfide isomerase (PDI) family, which plays a role in the regulation of protein homeostasis and the unfolded protein response pathway (UPR). AGR2 has also been characterized as a proto-oncogene and a potential cancer biomarker. Cellular localiz...

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Vydáno v:Oncogene
Hlavní autoři: Tiemann, Katrin, Garri, Carolina, Lee, Sang Bok, Malihi, Paymaneh D., Park, Mincheol, Alvarez, Ruth M., Yap, Li Peng, Mallick, Parag, Katz, Jonathan E., Gross, Mitchell E., Kani, Kian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523706/
https://ncbi.nlm.nih.gov/pubmed/30575818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0638-9
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