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Susceptibility of rat steatotic liver to ischemia-reperfusion is treatable with liver-selective matrix metalloproteinase inhibition

This study examined whether enhanced susceptibility of steatotic liver to I/R injury is due to impaired recruitment of bone marrow (BM) progenitors of LSECs (also called sprocs) with diminished repair of injured LSECs and whether restoring signaling to recruit BM sprocs reduces I/R injury. METHODS:...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Wang, Xiangdong, Walkey, Christopher J., Maretti-Mira, Ana C., Wang, Lei, Johnson, Deborah L., DeLeve, Laurie D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523533/
https://ncbi.nlm.nih.gov/pubmed/32060938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31179
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