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Susceptibility of rat steatotic liver to ischemia-reperfusion is treatable with liver-selective matrix metalloproteinase inhibition

This study examined whether enhanced susceptibility of steatotic liver to I/R injury is due to impaired recruitment of bone marrow (BM) progenitors of LSECs (also called sprocs) with diminished repair of injured LSECs and whether restoring signaling to recruit BM sprocs reduces I/R injury. METHODS:...

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Bibliographic Details
Published in:Hepatology
Main Authors: Wang, Xiangdong, Walkey, Christopher J., Maretti-Mira, Ana C., Wang, Lei, Johnson, Deborah L., DeLeve, Laurie D.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523533/
https://ncbi.nlm.nih.gov/pubmed/32060938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31179
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