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LIVER-SELECTIVE MMP-9 INHIBITION IN THE RAT ELIMINATES ISCHEMIA-REPERFUSION INJURY AND ACCELERATES LIVER REGENERATION
Recruitment of liver sinusoidal endothelial cell progenitor cells, so-called sprocs, from the bone marrow by VEGF-sdf1 signaling promotes recovery from injury and drives liver regeneration. Matrix metalloproteinases (MMPs) can proteolytically cleave VEGF, which might inhibit progenitor cell recruitm...
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| Publicado no: | Hepatology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6325019/ https://ncbi.nlm.nih.gov/pubmed/30019419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30169 |
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