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Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity

Models to study host-pathogen interactions in vitro are an important tool for investigating the infectious disease process and evaluating the efficacy of antimicrobial compounds. In these models, the viability of mammalian cells is often determined using the lactate dehydrogenase (LDH) cytotoxicity...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Van den Bossche, Sara, Vandeplassche, Eva, Ostyn, Lisa, Coenye, Tom, Crabbé, Aurélie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523407/
https://ncbi.nlm.nih.gov/pubmed/33042868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00494
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