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Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity

Models to study host-pathogen interactions in vitro are an important tool for investigating the infectious disease process and evaluating the efficacy of antimicrobial compounds. In these models, the viability of mammalian cells is often determined using the lactate dehydrogenase (LDH) cytotoxicity...

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Dettagli Bibliografici
Pubblicato in:Front Cell Infect Microbiol
Autori principali: Van den Bossche, Sara, Vandeplassche, Eva, Ostyn, Lisa, Coenye, Tom, Crabbé, Aurélie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523407/
https://ncbi.nlm.nih.gov/pubmed/33042868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00494
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