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Bacterial Interference With Lactate Dehydrogenase Assay Leads to an Underestimation of Cytotoxicity

Models to study host-pathogen interactions in vitro are an important tool for investigating the infectious disease process and evaluating the efficacy of antimicrobial compounds. In these models, the viability of mammalian cells is often determined using the lactate dehydrogenase (LDH) cytotoxicity...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Van den Bossche, Sara, Vandeplassche, Eva, Ostyn, Lisa, Coenye, Tom, Crabbé, Aurélie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523407/
https://ncbi.nlm.nih.gov/pubmed/33042868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00494
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