Lysyl oxidase like-2 contributes to renal fibrosis in Col4a3/Alport Mice.

Lysyl oxidase like-2 (LOXL2) is an amine oxidase with both intracellular and extracellular functions. Extracellularly, LOXL2 promotes collagen and elastin crosslinking, whereas intracellularly, LOXL2 has been reported to modify histone H3, stabilize SNAIL, and reduce cell polarity. LOXL2 promotes li...

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Udgivet i:Kidney Int
Main Authors: Cosgrove, Dominic, Dufek, Brianna, Meehan, Daniel T., Delimont, Duane, Hartnett, Michael, Samuelson, Gina, Gratton, Michael Anne, Phillips, Grady, MacKenna, Deidre A., Bain, Gretchen
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523185/
https://ncbi.nlm.nih.gov/pubmed/29759420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2018.02.024
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