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Discovery of human ACE2 variants with altered recognition by the SARS-CoV-2 spike protein
Understanding how human ACE2 genetic variants differ in their recognition by SARS-CoV-2 can have a major impact in leveraging ACE2 as an axis for treating and preventing COVID-19. In this work, we experimentally interrogate thousands of ACE2 mutants to identify over one hundred human single-nucleoti...
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| Published in: | bioRxiv |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523126/ https://ncbi.nlm.nih.gov/pubmed/32995796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.17.301861 |
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