The ACE2-binding Interface of SARS-CoV-2 Spike Inherently Deflects Immune Recognition

The COVID-19 pandemic remains a global threat, and host immunity remains the main mechanism of protection against the disease. The spike protein on the surface of SARS-CoV-2 is a major antigen and its engagement with human ACE2 receptor plays an essential role in viral entry into host cells. Consequ...

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Udgivet i:J Mol Biol
Main Authors: Hattori, Takamitsu, Koide, Akiko, Noval, Maria G., Panchenko, Tatyana, Romero, Larizbeth A., Teng, Kai Wen, Tada, Takuya, Landau, Nathaniel R., Stapleford, Kenneth A., Koide, Shohei
Format: Artigo
Sprog:Inglês
Udgivet: The Authors. Published by Elsevier Ltd. 2021
Fag:
Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833242/
https://ncbi.nlm.nih.gov/pubmed/33310017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.166748
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