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Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

SARS-CoV-2 causes the recent global COVID-19 public health emergency. ACE2 is the receptor for both SARS-CoV-2 and SARS-CoV. To predict the potential host range of SARS-CoV-2, we analyzed the key residues of ACE2 for recognizing S protein. We found that most of the selected mammals including pets (d...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Luan, Junwen, Lu, Yue, Jin, Xiaolu, Zhang, Leiliang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102515/
https://ncbi.nlm.nih.gov/pubmed/32201080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.03.047
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