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PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor
The Published Kinase Inhibitor Set (PKIS) is a publicly-available chemogenomic library distributed to more than 300 laboratories by GlaxoSmithKline (GSK) between 2011 and 2015 and by SGC-UNC from 2015 to 2017. Screening this library of well-annotated, published kinase inhibitors has yielded a pletho...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7522982/ https://ncbi.nlm.nih.gov/pubmed/32985588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72869-9 |
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