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PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer

The multifunctional protein Y-box binding protein 1 (YBX1), is a critical regulator of transcription and translation, and is widely recognized as an oncogenic driver in several solid tumors, including colorectal cancer (CRC). However, very little is known about the upstream or downstream factors tha...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Hartley, Antja-Voy, Wang, Benlian, Mundade, Rasika, Jiang, Guanglong, Sun, Mengyao, Wei, Han, Sun, Steven, Liu, Yunlong, Lu, Tao
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522246/
https://ncbi.nlm.nih.gov/pubmed/32985589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72942-3
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