Regulation of a PRMT5/NF-κB Axis by Phosphorylation of PRMT5 at Serine 15 in Colorectal Cancer

The overexpression of PRMT5 is highly correlated to poor clinical outcomes for colorectal cancer (CRC) patients. Importantly, our previous work demonstrated that PRMT5 overexpression could substantially augment activation of the nuclear factor kappa B (NF-κB) via methylation of arginine 30 (R30) on...

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Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Hartley, Antja-Voy, Wang, Benlian, Jiang, Guanglong, Wei, Han, Sun, Mengyao, Prabhu, Lakshmi, Martin, Matthew, Safa, Ahmad, Sun, Steven, Liu, Yunlong, Lu, Tao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279388/
https://ncbi.nlm.nih.gov/pubmed/32456215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103684
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