PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer

The multifunctional protein Y-box binding protein 1 (YBX1), is a critical regulator of transcription and translation, and is widely recognized as an oncogenic driver in several solid tumors, including colorectal cancer (CRC). However, very little is known about the upstream or downstream factors tha...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hartley, Antja-Voy, Wang, Benlian, Mundade, Rasika, Jiang, Guanglong, Sun, Mengyao, Wei, Han, Sun, Steven, Liu, Yunlong, Lu, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522246/
https://ncbi.nlm.nih.gov/pubmed/32985589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72942-3
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