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Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodeling
Tractional remodeling of collagen fibrils by fibroblasts requires long cell extensions that mediate fibril alignment. The formation of these cell extensions involves flightless I (FliI), an actin-binding protein that contains a leucine-rich-repeat (LRR), which binds R-ras and may regulate cdc42. We...
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| Publié dans: | Mol Biol Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Cell Biology
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7521798/ https://ncbi.nlm.nih.gov/pubmed/32432944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-10-0554 |
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