IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma

BACKGROUND: IQGAP1 and IQGAP2 are homologous members of the IQGAP family of scaffold proteins. Accumulating evidence implicates IQGAPs in tumorigenesis. We recently reported that IQGAP2 deficiency leads to the development of hepatocellular carcinoma (HCC) in mice. In the current study we extend thes...

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Detalhes bibliográficos
Main Authors: White, Colin D, Khurana, Hema, Gnatenko, Dmitri V, Li, Zhigang, Odze, Robert D, Sacks, David B, Schmidt, Valentina A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988069/
https://ncbi.nlm.nih.gov/pubmed/20977743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-125
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