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Salmonella typhimurium usurps the scaffold protein IQGAP1 to manipulate Rac1 and MAP kinase signaling
Salmonella typhimurium invades eukaryotic cells by re-arranging the host cell cytoskeleton. However, the precise mechanisms by which Salmonella induces cytoskeletal changes remain undefined. IQGAP1 is a scaffold protein that binds multiple proteins, including actin, the Rho GTPases Rac1 and Cdc42, a...
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| Udgivet i: | Biochem J |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4236857/ https://ncbi.nlm.nih.gov/pubmed/21851337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20110419 |
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