IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma

BACKGROUND: IQGAP1 and IQGAP2 are homologous members of the IQGAP family of scaffold proteins. Accumulating evidence implicates IQGAPs in tumorigenesis. We recently reported that IQGAP2 deficiency leads to the development of hepatocellular carcinoma (HCC) in mice. In the current study we extend thes...

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Autors principals: White, Colin D, Khurana, Hema, Gnatenko, Dmitri V, Li, Zhigang, Odze, Robert D, Sacks, David B, Schmidt, Valentina A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988069/
https://ncbi.nlm.nih.gov/pubmed/20977743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-125
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