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Parietal epithelial cell differentiation to a podocyte fate in the aged mouse kidney

Healthy aging is typified by a progressive and absolute loss of podocytes over the lifespan of animals and humans. To test the hypothesis that a subset of glomerular parietal epithelial cell (PEC) progenitors transition to a podocyte fate with aging, dual reporter PEC-rtTA|LC1|tdTomato|Nphs1-FLPo|FR...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Kaverina, Natalya V., Eng, Diana G., Miner, Jeffrey H., Pippin, Jeffrey W., Shankland, Stuart J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521511/
https://ncbi.nlm.nih.gov/pubmed/32858527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103788
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