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Reducing mTOR augments parietal epithelial cell density in a model of acute podocyte depletion and in aged kidneys
Parietal epithelial cell (PEC) response to glomerular injury may underlie a common pathway driving fibrogenesis following podocyte loss that typifies several glomerular disorders. Although the mammalian target of rapamycin (mTOR) pathway is important in cell homeostasis, little is known of the biolo...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142165/ https://ncbi.nlm.nih.gov/pubmed/27440779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00196.2016 |
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