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Reducing mTOR augments parietal epithelial cell density in a model of acute podocyte depletion and in aged kidneys

Parietal epithelial cell (PEC) response to glomerular injury may underlie a common pathway driving fibrogenesis following podocyte loss that typifies several glomerular disorders. Although the mammalian target of rapamycin (mTOR) pathway is important in cell homeostasis, little is known of the biolo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Am J Physiol Renal Physiol
Päätekijät: McNicholas, Bairbre A., Eng, Diana G., Lichtnekert, Julia, Rabinowitz, Peter S., Pippin, Jeffrey W., Shankland, Stuart J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142165/
https://ncbi.nlm.nih.gov/pubmed/27440779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00196.2016
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