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Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans

Aging is the primary driver of various diseases, including common neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Currently there is no cure for AD and PD, and the development of novel drug candidates is demanding. Spermidine is a small anti-aging molecule w...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Yang, Xin, Zhang, Mohan, Dai, Yuhua, Sun, Yuchao, Aman, Yahyah, Xu, Yuying, Yu, Peilin, Zheng, Yifan, Yang, Jun, Zhu, Xinqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521492/
https://ncbi.nlm.nih.gov/pubmed/32902411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103578
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