Spermidine inhibits neurodegeneration and delays aging via the PINK1-PDR1-dependent mitophagy pathway in C. elegans

Aging is the primary driver of various diseases, including common neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Currently there is no cure for AD and PD, and the development of novel drug candidates is demanding. Spermidine is a small anti-aging molecule w...

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Опубликовано в: :Aging (Albany NY)
Главные авторы: Yang, Xin, Zhang, Mohan, Dai, Yuhua, Sun, Yuchao, Aman, Yahyah, Xu, Yuying, Yu, Peilin, Zheng, Yifan, Yang, Jun, Zhu, Xinqiang
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals 2020
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521492/
https://ncbi.nlm.nih.gov/pubmed/32902411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103578
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