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Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation

Clonal hematopoiesis is associated with various age-related morbidities. Error-corrected sequencing (ECS) of human blood samples, with a limit of detection of ≥0.0001, has demonstrated that nearly every healthy individual >50 years old harbors rare hematopoietic clones below the detection limit o...

詳細記述

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書誌詳細
出版年:Sci Transl Med
主要な著者: Wong, Wing Hing, Bhatt, Sima, Trinkaus, Kathryn, Pusic, Iskra, Elliott, Kevin, Mahajan, Nitin, Wan, Fei, Switzer, Galen E., Confer, Dennis L., DiPersio, John, Pulsipher, Michael A., Shah, Nirali N., Sees, Jennifer, Bystry, Amelia, Blundell, Jamie R., Shaw, Bronwen E., Druley, Todd E.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521140/
https://ncbi.nlm.nih.gov/pubmed/31941826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aax6249
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