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Nonenzymatic, Self-Elimination Degradation Mechanism of Glutathione
In the present in vitro studies, evidence is provided showing that glutathione (GSH) can undergo spontaneous, nonenzymatic auto-degradation. The initial cleavage of the Glu-Cys bond involves nucleophilic attack of the N-terminal amino group of GSH at the γ-carbonyl side chain, followed by an unusual...
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| Udgivet i: | Chem Biodivers |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7521115/ https://ncbi.nlm.nih.gov/pubmed/19353534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbdv.200800277 |
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