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Pulmonary targeting microparticulate camptothecin delivery system: anti-cancer evaluation in a rat orthotopic lung cancer model

Large (>6 µm) rigid microparticles (MPs) become passively entrapped within the lungs following intravenous injection making them an attractive and highly efficient alternative to inhalation for pulmonary delivery. In the current studies, PEGylated 6 μm polystyrene MPs with multiple copies of the...

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Bibliographische Detailangaben
Hauptverfasser: Chao, Piyun, Deshmukh, Manjeet, Kutscher, Hilliard L., Gao, Dayuan, Sundara Rajan, Sujata, Hu, Peidi, Laskin, Debra L., Stein, Stanley, Sinko, Patrick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859198/
https://ncbi.nlm.nih.gov/pubmed/19966540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e328332a322
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