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Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy

The widespread application of immune-checkpoint blockade (ICB) has resulted in unprecedented response rates in patients with immunogenic cancers, such as melanoma and lung cancer. However, sub-groups of patients with these indications do not respond to ICB, and the same applies to patients with othe...

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Publicat a:Cell Stress
Autors principals: Baumann, Daniel, Offringa, Rienk
Format: Artigo
Idioma:Inglês
Publicat: Shared Science Publishers OG 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520667/
https://ncbi.nlm.nih.gov/pubmed/33024933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/cst2020.10.233
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