Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy

Cancer types with lower mutational load and a non-permissive tumor microenvironment are intrinsically resistant to immune checkpoint blockade. While the combination of cytostatic drugs and immunostimulatory antibodies constitutes an attractive concept for overcoming this refractoriness, suppression...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Baumann, Daniel, Hägele, Tanja, Mochayedi, Julian, Drebant, Jennifer, Vent, Caroline, Blobner, Sven, Noll, Julia Han, Nickel, Irena, Schumacher, Corinna, Boos, Sophie Luise, Daniel, Aline Sophie, Wendler, Susann, Volkmar, Michael, Strobel, Oliver, Offringa, Rienk
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7195409/
https://ncbi.nlm.nih.gov/pubmed/32358491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15979-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker