Exon 11 homozygous mutations and intron 10/exon 11 junction deletions in the KIT gene are associated with poor prognosis of patients with gastrointestinal stromal tumors

BACKGROUND: Gastrointestinal stromal tumors (GISTs) with different types of mutations exhibit different clinical characteristics and prognosis. This study aimed to evaluate the prognostic value of mutations in KIT and PDGFRA in a large‐scale cohort of GIST patients with current therapy including sur...

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Vydáno v:Cancer Med
Hlavní autoři: Shen, Yan‐Ying, Ma, Xin‐Li, Wang, Ming, Zhuang, Chun, Ni, Bo, Tu, Lin, Liu, Qiang, Zhao, Wen‐Yi, Cao, Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Clinical Cancer Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520349/
https://ncbi.nlm.nih.gov/pubmed/32697050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3212
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