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Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are common mesenchymal neoplasms in the gastrointestinal tract of humans and dogs. Little is known about the pathogenesis of these tumors. This study evaluated the role of c-KIT in canine GISTs; specifically, we investigated activating mutations in...

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Détails bibliographiques
Auteurs principaux: Gregory-Bryson, Emmalena, Bartlett, Elizabeth, Kiupel, Matti, Hayes, Schantel, Yuzbasiyan-Gurkan, Vilma
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970610/
https://ncbi.nlm.nih.gov/pubmed/20950418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-559
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