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Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are common mesenchymal neoplasms in the gastrointestinal tract of humans and dogs. Little is known about the pathogenesis of these tumors. This study evaluated the role of c-KIT in canine GISTs; specifically, we investigated activating mutations in...

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Autori principali: Gregory-Bryson, Emmalena, Bartlett, Elizabeth, Kiupel, Matti, Hayes, Schantel, Yuzbasiyan-Gurkan, Vilma
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970610/
https://ncbi.nlm.nih.gov/pubmed/20950418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-559
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