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Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11

BACKGROUND: Gastrointestinal stromal tumors (GISTs) are common mesenchymal neoplasms in the gastrointestinal tract of humans and dogs. Little is known about the pathogenesis of these tumors. This study evaluated the role of c-KIT in canine GISTs; specifically, we investigated activating mutations in...

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Bibliografiske detaljer
Main Authors: Gregory-Bryson, Emmalena, Bartlett, Elizabeth, Kiupel, Matti, Hayes, Schantel, Yuzbasiyan-Gurkan, Vilma
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970610/
https://ncbi.nlm.nih.gov/pubmed/20950418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-559
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