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Mechanistic insights into the effects of SREBP1c on hepatic stellate cell and liver fibrosis

Sterol regulatory element‐binding protein 1c (SREBP1c) plays key roles in maintenance of hepatic stellate cell (HSC) quiescence. The present researches investigated the mechanisms underlying the effects of SREBP1c on HSCs and liver fibrogenesis by HSC‐targeted overexpression of the active SREBP1c us...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Su, Shengyan, Tian, Haimeng, Jia, Xin, Zhu, Xiaofei, Wu, Juanjuan, Zhang, Yali, Chen, Yuanyuan, Li, Ziqiang, Zhou, Yajun
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520338/
https://ncbi.nlm.nih.gov/pubmed/32678475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15614
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