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Hepatic stellate cells as key target in liver fibrosis

Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more than one million deaths annually via development of cirrhosis, although no antifibrotic therapy has been approved to date. Transdifferentiation (or “activation”) of hepatic stellate cells is the major cellula...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Higashi, Takaaki, Friedman, Scott L., Hoshida, Yujin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682243/
https://ncbi.nlm.nih.gov/pubmed/28506744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2017.05.007
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