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Induction and Contribution of β-PDGFR Signaling by Hepatic Stellate Cells to Liver Regeneration after Partial Hepatectomy in Mice

BACKGROUND: Hepatic stellate cells (HSCs) activate during injury to orchestrate the liver’s inflammatory and fibrogenic responses. A critical feature of HSC activation is the rapid induction of β-PDGFR, which drives cellular fibrogenesis and proliferation; in contrast, normal liver has minimal β-PDG...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Kocabayoglu, Peri, Zhang, David Y., Kojima, Kensuke, Hoshida, Yujin, Friedman, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749477/
https://ncbi.nlm.nih.gov/pubmed/26256287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.12933
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