Endothelial Overexpression of Metallothionein Prevents Diabetes-Induced Impairment in Ischemia Angiogenesis Through Preservation of HIF-1α/SDF-1/VEGF Signaling in Endothelial Progenitor Cells

Diabetes-induced oxidative stress is one of the major contributors to dysfunction of endothelial progenitor cells (EPCs) and impaired endothelial regeneration. Thus, we tested whether increasing antioxidant protein metallothionein (MT) in EPCs promotes angiogenesis in a hind limb ischemia (HLI) mode...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Wang, Kai, Dai, Xiaozhen, He, Junhong, Yan, Xiaoqing, Yang, Chengkui, Fan, Xia, Sun, Shiyue, Chen, Jing, Xu, Jianxiang, Deng, Zhongbin, Fan, Jiawei, Yuan, Xiaohuan, Liu, Hairong, Carlson, Edward C., Shen, Feixia, Wintergerst, Kupper A., Conklin, Daniel J., Epstein, Paul N., Lu, Chaosheng, Tan, Yi
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2020
Fag:
Complications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519474/
https://ncbi.nlm.nih.gov/pubmed/32404351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0829
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker