Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation

BACKGROUND: Mitochondrial succinate accumulation has been suggested as key event for ischemia reperfusion injury in mice. No specific data are however available on behavior of liver mitochondria during ex situ machine perfusion in clinical transplant models. METHODS: We investigated mitochondrial me...

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Publicat a:EBioMedicine
Autors principals: Schlegel, Andrea, Muller, Xavier, Mueller, Matteo, Stepanova, Anna, Kron, Philipp, de Rougemont, Olivier, Muiesan, Paolo, Clavien, Pierre-Alain, Galkin, Alexander, Meierhofer, David, Dutkowski, Philipp
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519249/
https://ncbi.nlm.nih.gov/pubmed/32979838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103014
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