Hypothermic oxygenated perfusion protects from mitochondrial injury before liver transplantation

BACKGROUND: Mitochondrial succinate accumulation has been suggested as key event for ischemia reperfusion injury in mice. No specific data are however available on behavior of liver mitochondria during ex situ machine perfusion in clinical transplant models. METHODS: We investigated mitochondrial me...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Schlegel, Andrea, Muller, Xavier, Mueller, Matteo, Stepanova, Anna, Kron, Philipp, de Rougemont, Olivier, Muiesan, Paolo, Clavien, Pierre-Alain, Galkin, Alexander, Meierhofer, David, Dutkowski, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519249/
https://ncbi.nlm.nih.gov/pubmed/32979838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103014
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