Circulation of gut-preactivated naïve CD8(+) T cells enhances antitumor immunity in B cell-defective mice

The gut microbiome has garnered attention as an effective target to boost immunity and improve cancer immunotherapy. We found that B cell-defective (BCD) mice, such as µ-membrane targeted deletion (µMT) and activation-induced cytidine deaminase (AID) knockouts (KOs), have elevated antitumor immunity...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Akrami, Maryam, Menzies, Rosemary, Chamoto, Kenji, Miyajima, Michio, Suzuki, Ryuji, Sato, Hiroyuki, Nishii, Akiko, Tomura, Michio, Fagarasan, Sidonia, Honjo, Tasuku
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2020
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519229/
https://ncbi.nlm.nih.gov/pubmed/32907933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010981117
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires