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Circulation of gut-preactivated naïve CD8(+) T cells enhances antitumor immunity in B cell-defective mice
The gut microbiome has garnered attention as an effective target to boost immunity and improve cancer immunotherapy. We found that B cell-defective (BCD) mice, such as µ-membrane targeted deletion (µMT) and activation-induced cytidine deaminase (AID) knockouts (KOs), have elevated antitumor immunity...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7519229/ https://ncbi.nlm.nih.gov/pubmed/32907933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010981117 |
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