PIK3R3 inhibits cell senescence through p53/p21 signaling

Cellular senescence is a stress response of human cells that removes potentially harmful cells by initiating cell cycle arrest. Inducing senescence of tumor cells may be an effective tumor-inhibiting strategy. In this study we found that PIK3R3 could inhibit the cell senescence of colorectal cancer...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Chen, Qianzhi, Sun, Xuling, Luo, Xuelai, Wang, Jing, Hu, Junbo, Feng, Yongdong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519147/
https://ncbi.nlm.nih.gov/pubmed/32973127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-02921-z
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