Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway

Brahma-related gene-1 (BRG1) is the specific ATPase of switch/sucrose nonfermentable chromatin-remodeling complex that is aberrantly expressed or mutated in various cancers. However, the exact role of BRG1 in oncogenesis remains unknown. In this study, we demonstrate that the knockdown (KD) of BRG1...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Wang, Guihua, Fu, Yinjia, Hu, Fuqing, Lan, Jinqing, Xu, Feng, Yang, Xi, Luo, Xuelai, Wang, Jing, Hu, Junbo
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386468/
https://ncbi.nlm.nih.gov/pubmed/28182012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.1
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