TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling

BACKGROUND: Cellular senescence is a state of irreversible cell growth arrest and senescence cells permanently lose proliferation potential. Induction of cellular senescence might be a novel therapy for cancer cells. TRIB2 has been reported to participate in regulating proliferation and drug resista...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cancer
Egile Nagusiak: Hou, Zhenlin, Guo, Kaixuan, Sun, Xuling, Hu, Fuqing, Chen, Qianzhi, Luo, Xuelai, Wang, Guihua, Hu, Junbo, Sun, Li
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291992/
https://ncbi.nlm.nih.gov/pubmed/30541550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0922-x
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