Inhibition of SIRT2 limits tumour angiogenesis via inactivation of the STAT3/VEGFA signalling pathway

Mounting evidence has demonstrated that angiogenesis plays an important role in tumour progression. However, the key regulators in tumour angiogenesis remain unclear. Recently, emerging reports have indicated that SIRT2 plays critical roles in proliferation, metastasis and tumourigenesis in diverse...

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Опубликовано в: :Cell Death Dis
Главные авторы: Hu, Fuqing, Sun, Xuling, Li, Geng, Wu, Qi, Chen, Yaqi, Yang, Xi, Luo, Xuelai, Hu, Junbo, Wang, Guihua
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315023/
https://ncbi.nlm.nih.gov/pubmed/30584257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1260-z
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