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New in vitro highly cytotoxic platinum and palladium cyanoximates with minimal side effects in vivo

Several biologically active bivalent Pd and Pt complexes with two structurally similar cyanoxime ligands abbreviated as H(DECO): 2-oximino-2-cyano-N,N′-diethylacetamide, and H(PyrCO): 2-oximino-2-cyan-N-pyrrolidine acetamide were synthesized and characterized using spectroscopic methods, thermal ana...

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Detalhes bibliográficos
Publicado no:J Inorg Biochem
Main Authors: Dannen, Stephanie D., Cornelison, Lauren, Durham, Paul, Morley, John E., Shahverdi, Kiana, Du, Junwei, Zhou, Haiying, Sudlow, Leland C., Hunter, Daniel, Wood, Matthew D., Berezin, Mikhail Y., Gerasimchuk, Nikolay
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518941/
https://ncbi.nlm.nih.gov/pubmed/32413634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2020.111082
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