New in vitro highly cytotoxic platinum and palladium cyanoximates with minimal side effects in vivo

Several biologically active bivalent Pd and Pt complexes with two structurally similar cyanoxime ligands abbreviated as H(DECO): 2-oximino-2-cyano-N,N′-diethylacetamide, and H(PyrCO): 2-oximino-2-cyan-N-pyrrolidine acetamide were synthesized and characterized using spectroscopic methods, thermal ana...

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Vydáno v:J Inorg Biochem
Hlavní autoři: Dannen, Stephanie D., Cornelison, Lauren, Durham, Paul, Morley, John E., Shahverdi, Kiana, Du, Junwei, Zhou, Haiying, Sudlow, Leland C., Hunter, Daniel, Wood, Matthew D., Berezin, Mikhail Y., Gerasimchuk, Nikolay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518941/
https://ncbi.nlm.nih.gov/pubmed/32413634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2020.111082
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